SeSaM-Biotech is dedicated to the Directed Evolution of enzymes. Our comprehensive evolution strategy KnowVolution as part of the QuESt-Service offers the best combination of patented mutagenesis technologies and rational design by computational modelling and simulations to successfully increase your enzyme’s performance. SeSaM-Biotech tunes enzyme properties like activity, ther­mal resilience, protease resistance, solvent/ pH stability, and substrate/product inhibi­tion.